• Dynamic self-organisation of haematopoiesis and (a)symmetric cell division 

      Måløy, Marthe; Måløy, Frode; Jakobsen, Per; Brandsdal, Bjørn Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-05)
      A model of haematopoiesis that links self-organisation with symmetric and asymmetric cell division is presented in this paper. It is assumed that all cell divisions are completely random events, and that the daughter cells resulting from symmetric and asymmetric stem cell divisions are, in general, phenotypically identical, and still, the haematopoietic system has the flexibility to self-renew, ...
    • Probability mapping of scarred myocardium using texture and intensity features in CMR images 

      Kotu, Lasya Priya; Engan, Kjersti; Skretting, Karl; Måløy, Frode; Ørn, Stein; Woie, Leik; Eftestøl, Trygve (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The myocardium exhibits heterogeneous nature due to scarring after Myocardial Infarction (MI). In Cardiac Magnetic Resonance (CMR) imaging, Late Gadolinium (LG) contrast agent enhances the intensity of scarred area in the myocardium. In this paper, we propose a probability mapping technique using Texture and Intensity features to describe heterogeneous nature of the scarred myocardium in Cardiac ...
    • Stem cell regulation: Implications when differentiated cells regulate symmetric stem cell division 

      Høyem, Marte Rørvik; Måløy, Frode; Jakobsen, Per; Brandsdal, Bjørn Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-19)
      We use a mathematical model to show that if symmetric stem cell division is regulated by differentiated cells, then changes in the population dynamics of the differentiated cells can lead to changes in the population dynamics of the stem cells. More precisely, the relative fitness of the stem cells can be affected by modifying the death rate of the differentiated cells. This result is interesting ...